UW School of Dentistry

Derrick Wang

Dr. Derrick Wang received his bachelor’s degree in Biochemistry from the University of California, Riverside. He went on to earn his Doctor of Dental Medicine from the University of Pennsylvania, School of Dental Medicine, in 1997. Upon graduation, Dr. Wang completed a General Practice Residency at York Hospital in York, Pennsylvania. During the first 10 years of Dr. Wang’s professional career, he maintained a private practice in aesthetic and general dentistry in York, Pennsylvania, and he remained on the medical staff at the York Hospital and Apple Hill Surgical Center where he performed dental rehabilitations under general anesthesia. He is the past president of York County Dental Society.

Dr. Wang then returned to the University of Pennsylvania, School of Dental Medicine, to complete his specialty training in Endodontics. He was subsequently chosen to teach at the Penn Dental Microscope Training Center where dentists from around the world come to learn micro-endodontics and microsurgery. Dr. Wang continues to maintain his appointment as an Adjunct Assistant Professor for the Department of Endodontics at the University of Pennsylvania.

In 2009, he relocated to Seattle and opened an endodontic practice in Redmond, Washington. Dr. Wang joined the faculty at the University of Washington, Department of Endodontics five years later, in 2016. He has served on numerous AAE (American Association of Endodontists) committees, as both an appointed member and as chair.

Dr. Wang specializes in endodontic microsurgery.

Natasha M. Flake

Endo-faculty

Dr. Flake is a member of the American Association of Endodontists, the American Association of Women Dentists, the International Association of Dental Research, the American Pain Society, the Society for Neuroscience and the American Dental Association.

Dr. Natasha Flake graduated Magna Cum Laude with a Doctor of Dental Surgery degree from the Baltimore College of Dental Surgery at the University of Maryland in 2005, with a Doctor of Philosophy in Biomedical Sciences from the University of Maryland Graduate School. Dr. Flake earned a Master of Science in Dentistry and Certificate in Endodontics from the University of Washington Graduate Endodontics Program in June 2007. She joined the faculty at the University of Washington School of Dentistry upon her graduation.

Mechanisms of nociception, pain, and analgesia
  1. Thut PD, Hermanstyne TO, Flake NM, and Gold MS. An operant conditioning model to assess changes in feeding behavior associated with temporomandibular joint inflammation in the rat. J Orofac Pain 2007 Winter; 21(1): 7-18.
  2. Flake NM, Hermanstyne TO, and Gold MS. Testosterone and estrogen have opposing actions on plasma extravasation in the rat temporomandibular joint. Am J Physiol Regul Integr Comp Physiol 2006 August; 291(2): R343-8. Read more…
  3. Gold MS and Flake NM. Inflammation-mediated hyperexcitability of sensory neurons. Neurosignals 2005; 14(4): 147-57.
  4. Flake NM and Gold MS. Inflammation alters sodium currents and excitability of temporomandibular joint afferents. Neurosci Lett 2005 August; 384(3): 294-9.
  5. Flake NM and Gold MS. Estrogen and inflammation increase the excitability of rat temporomandibular joint afferent neurons. J Neurophys 2005 March; 93(3): 1585-97. Read more…
  6. Flake NM, Lancaster E, Weinreich D, and Gold MS. Absence of an association between axotomy-induced changes in sodium currents and excitability in DRG neurons from the adult rat. Pain 2004 June; 109(1): 471-80. Read more…
  7. Divine JK, Flake NM, Sheehan K, and Gottlieb DI. Expression of a novel antigen, EEM-1, in the mouse embryo and embryonic stem cell-derived embryoid bodies. Developmental Dynamics 2000 May; 218(1): 207-11

James D. Johnson

Background

Dr. Johnson was appointed Chair of the Endodontics Department at the School of Dentistry at the University of Washington in 2003. He also serves as the Program Director for the Advanced Specialty Education Program in Endodontics at the University of Washington as a Clinical Associate Professor. Dr. Johnson retired from the U.S. Navy Dental Corps in 2003 at the rank of Captain. Dr. Johnson reported to the faculty of the Endodontics Department of the Naval Postgraduate Dental School in July 1994. He assumed the position as Chairman of the Endodontics Department and Director of the Advanced Specialty Education Program in Endodontics at the Naval Postgraduate Dental School in 1997, and held that post until 2001.

Additionally, he served as Specialty Leader for Endodontics, Bureau of Medicine and Surgery to the Surgeon General of the Navy. Dr. Johnson served as Chair, Research Department, at the Naval Postgraduate Dental School in Bethesda, Maryland from 2001 to 2003.

Dr. Johnson attended the University of Colorado as an undergraduate and received his DDS degree from Northwestern University Dental School. Upon graduation he was commissioned as a Dental Officer in the U.S. Air Force, serving at the USAF Regional Hospital, March AFB, California; the 483rd USAF Hospital in the Republic of Viet Nam; and the USAF Dispensary at Ent AFB, Colorado. Dr. Johnson went into private practice in Colorado before returning to Northwestern University Dental School to earn a Certificate in Endodontics and a M.S. degree in 1985.

Dr. Johnson returned to active duty in the Navy after completion of his residency. He has served as the Head of the Endodontics Department at these duty stations: Naval Dental Clinic, Camp Lejeune, NC; the 2nd Dental Company, Camp Lejeune, NC; and at the Branch Dental Clinic Washington Navy Yard, Washington DC. Dr. Johnson is a Diplomate of the American Board of Endodontics. He is a member of the American Dental Association, the American Association of Endodontists, the College of Diplomates of the American Board of Endodontics, the American Dental Education Association, the International Association of Dental Research, the International Association of Dental Traumatology, and is past president of the U.S. Navy Association of Endodontists, and past president of the Edward C. Penick Endodontic Study Club, and past president of the Coastal Carolina Dental Society. He is also a member of the Seattle – King County Dental Society, the Washington State Dental Association, and the Washington State Association of Endodontists.

Additionally, he serves as a consultant for Endodontics for the Commission on Dental Accreditation for the American Dental Association. He is an officer on the Board of the Washington State Association of Endodontists. He is a Fellow in the International College of Dentists. Dr. Johnson’s research and academic interests include surgical and nonsurgical endodontics, pulpal / periradicular biology and pathology, instrumentation of the root canal system. He has published numerous scientific papers, and has lectured in the United States, and Europe.

Avina Paranjpe

Dr. Paranjpe is a member of the American Association of Endodontists (AAE), American Dental Association (ADA) and the International Association of Dental Research (IADR).

Endo-faculty

Dr. Avina Paranjpe graduated with her BDS (Bachelor of Dental Surgery) degree from the Mumbai University, India in 2000. She was in private practice in Mumbai, India from 2000-2002 after which she obtained her Master’s degree (MS) and a Doctor of Philosophy (PhD) in Oral Biology, Immunology from the University of California, Los Angeles in 2004 and 2007 respectively. Dr. Paranjpe earned her Master of Science in Dentistry (MSD) and Certificate in Endodontics from the University of Washington Graduate Endodontics Program in August 2009 after which she joined the faculty at the University of Washington, School of Dentistry as Assistant Professor. She is a Diplomate of the American Board of Endodontics. Dr. Paranjpe is involved in several ongoing research projects related to dental materials and regenerative Endodontics. She has numerous publications in the area of pulpal regeneration and revascularization, immunology, compatibility of biomaterials.

Pulpal regeneration and revascularization, immunology, compatibility of biomaterials
  1. Paranjpe A, Cacalano N,  Hume WR., Jewett A. N-acetyl cysteine (NAC) mediates protection from 2-Hydroxyethyl methacrylate (HEMA) induced apoptosis via NFkB dependent and independent pathways: Potential involvement of JNK. Toxicological Sciences 2009 Apr;108(2):356-66. Read more…
  2. Cacalano NA, Le D, Paranjpe A, Wang MY, Fernandez A, Evazyan T, Park NH, Jewett A : Regulation of IGFBP6 gene and protein is mediated by the inverse expression and function of c-jun N-terminal kinase (JNK) and NFkappaB in a model of oral tumor cells. Apoptosis. 2008 Dec;13(12):1439-49. Read more…
  3. Kojima N, Yamada M, Paranjpe A, Tsukimura N, Kubo K, Jewett A, Ogawa T. Restored viability and function of dental pulp cells on poly-methylmethacrylate (PMMA)-based dental resin supplemented with n-acetyl cysteine (NAC). Dental Materials 2008 Dec;24(12):1686-93.
  4. Yamada M, Kojima N, Paranjpe A, Att W, Aita H, Jewett A, Ogawa T. N-acetyl cysteine (nac)-assisted detoxification of pmma resin. Journal  of Dental  Research  2008;87:372-7. Read more…
  5. Paranjpe A, Cacalano N,  Hume WR., Jewett A. Mechanisms of N-acetyl cysteine mediated protection from 2-Hydroxyethyl methacrylate (HEMA) induced apoptosis. Journal of Endodontics 2008;34(10):1191-7. Read more…
  6. Paranjpe A, Sung EC, Cacalano NA, Hume WR, Jewett A. N-acetyl cysteine protects pulp cells from resin toxins in vivo. Journal of  Dental Research 2008;87:537-41. Read more…
  7. Paranjpe A, Cacalano NA, Hume WR, Jewett A. N-acetylcysteine protects dental pulp stromal cells from HEMA-induced apoptosis by inducing differentiation of the cells. Free Radic Biol Med 2007;43:1394-408.
  8. Paranjpe A, L.C.F. Bordador, M.-y. Wang, W.R. Hume, and A. Jewett : Resin Monomer 2-Hydroxyethyl Methacrylate (HEMA) is a Potent Inducer of Apoptotic Cell Death in Human and Mouse Cells :  Journal of Dental Research 84(2):172-177, 2005. Read more…