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Avina Paranjpe, BDS, MS, MSD, PhD

Avina Paranjpe

Professor, Endodontics
Graduate Program Director
Director: International Dental Program


Dr. Paranjpe is a member of the American Association of Endodontists (AAE), American Dental Association (ADA) and the International Association of Dental Research (IADR).


Dr. Avina Paranjpe graduated with her BDS (Bachelor of Dental Surgery) degree from the Mumbai University, India in 2000. She was in private practice in Mumbai, India from 2000-2002 after which she obtained her Master’s degree (MS) and a Doctor of Philosophy (PhD) in Oral Biology, Immunology from the University of California, Los Angeles in 2004 and 2007 respectively. Dr. Paranjpe earned her Master of Science in Dentistry (MSD) and Certificate in Endodontics from the University of Washington Graduate Endodontics Program in August 2009 after which she joined the faculty at the University of Washington, School of Dentistry as Assistant Professor. She is a Diplomate of the American Board of Endodontics. Dr. Paranjpe is involved in several ongoing research projects related to dental materials and regenerative Endodontics. She has numerous publications in the area of pulpal regeneration and revascularization, immunology, compatibility of biomaterials.

Pulpal regeneration and revascularization, immunology, compatibility of biomaterials
  1. Paranjpe A, Cacalano N,  Hume WR., Jewett A. N-acetyl cysteine (NAC) mediates protection from 2-Hydroxyethyl methacrylate (HEMA) induced apoptosis via NFkB dependent and independent pathways: Potential involvement of JNK. Toxicological Sciences 2009 Apr;108(2):356-66. Read more…
  2. Cacalano NA, Le D, Paranjpe A, Wang MY, Fernandez A, Evazyan T, Park NH, Jewett A : Regulation of IGFBP6 gene and protein is mediated by the inverse expression and function of c-jun N-terminal kinase (JNK) and NFkappaB in a model of oral tumor cells. Apoptosis. 2008 Dec;13(12):1439-49. Read more…
  3. Kojima N, Yamada M, Paranjpe A, Tsukimura N, Kubo K, Jewett A, Ogawa T. Restored viability and function of dental pulp cells on poly-methylmethacrylate (PMMA)-based dental resin supplemented with n-acetyl cysteine (NAC). Dental Materials 2008 Dec;24(12):1686-93.
  4. Yamada M, Kojima N, Paranjpe A, Att W, Aita H, Jewett A, Ogawa T. N-acetyl cysteine (nac)-assisted detoxification of pmma resin. Journal  of Dental  Research  2008;87:372-7. Read more…
  5. Paranjpe A, Cacalano N,  Hume WR., Jewett A. Mechanisms of N-acetyl cysteine mediated protection from 2-Hydroxyethyl methacrylate (HEMA) induced apoptosis. Journal of Endodontics 2008;34(10):1191-7. Read more…
  6. Paranjpe A, Sung EC, Cacalano NA, Hume WR, Jewett A. N-acetyl cysteine protects pulp cells from resin toxins in vivo. Journal of  Dental Research 2008;87:537-41. Read more…
  7. Paranjpe A, Cacalano NA, Hume WR, Jewett A. N-acetylcysteine protects dental pulp stromal cells from HEMA-induced apoptosis by inducing differentiation of the cells. Free Radic Biol Med 2007;43:1394-408.
  8. Paranjpe A, L.C.F. Bordador, M.-y. Wang, W.R. Hume, and A. Jewett : Resin Monomer 2-Hydroxyethyl Methacrylate (HEMA) is a Potent Inducer of Apoptotic Cell Death in Human and Mouse Cells :  Journal of Dental Research 84(2):172-177, 2005. Read more…