UW School of Dentistry


HPV-Induced Benign & Malignant Oral Lesions

Dolphine Oda, BDS, MS

Monday evening, September 22, 2014

University of Washington
Health Sciences Building, D-209
Seattle, Washington 98195
Online as a live webinar**

This course is designed for dentists, hygienists and dental assistants.

Download Course Application Form
Register Online (available until two days before the course).

Registration and Lite Dinner:
6:00pm – 6:30pm
Course: 6:30pm – 8:30pm

TUITION – price includes lite dinner:
Until September 19, 2014 (after, $25 more)
$67/Current Dental Alumni Member

CREDITS: 2 hours

* This course is eligible for a 10% tuition discount if you are a current member of the UW Dental Alumni Association.

*** Washington State Dentists – please note that per WAC 246-817-440(c), you may only count 7 CDE hours each year earned through educational audio or videotapes, films, slides, internet, or independent reading toward your annual CDE requirement.

Course Description

Human papillomaviruses (HPVs) are a group of small, species specific, double-stranded DNA viruses that specifically infect epithelial cells of the skin and mucosa, including the oral mucosa. Over 130 types of HPV are described; these are divided into low- and high-risk categories. Low-risk types of HPV are associated with venereal and common warts and focal epithelial hyperplasia (Heck’s disease). High-risk HPVs, also known as oncogenic HPVs, are associated with cervical, oral and oropharyngeal, anal, vaginal, vulvar and penile squamous cell carcinomas (SCCs). In 2009, a cross-sectional study of the prevalence of oral HPV infection demonstrated that 6.9% of the US population between the ages of 14-69 has HPV in their mouth and that 1% had the oncogenic HPV type 16. The study also showed that HPV is three times as prevalent in males as in females (10.1% vs. 3.6%), which corresponds to the significantly more common clinical incidence of oropharyngeal SCC in males.

This two-hour lecture will discuss the different types of HPV and their pathogenesis into producing benign and malignant oral diseases. It will also discuss in depth the role of HPV in oropharyngeal SCC and its relation to cervical cancer. In addition, this lecture will address the life cycle of the virus and the effect of immunization on the variant HPV-associated cancers. Part of the focus will be on the clinical presentation and patient profile of oral HPV-induced benign and malignant lesions. Testing for HPV in the mouth will also be discussed.

Course Objectives

As a result of attending this course, you will be able to:

  • Understand the prevalence of oral HPV in the general population
  • Learn about the life cycle of the virus and how it transforms epithelial cells
  • Differentiate between low-risk and high-risk HPV types
  • Identify oral benign lesions associated with HPV
  • Understand the role of HPV in oral SCC
  • Differentiate between the clinical presentation of HPV-induced and tobacco-induced oral SCC
  • Understand the different types of testing for oral HPV


Dr. Oda

DOLPHINE ODA is a Professor of Oral Pathology in the Department of Oral and Maxillofacial Surgery at the School of Dentistry, University of Washington, and the director of the UW’s Oral Pathology Biopsy Service. Dr. Oda is on the medical staff at the University of Washington Medical Center and Harborview Medical Center. In 2013, she was awarded a lifetime achievement award by the Oral Cancer Foundation for over 30 years of service to oral cancer patients. In 2009, she was awarded the Distinguished Teaching Award, the UW’s highest honor for outstanding teaching, and has been awarded an additional 28 teaching awards within the School of Dentistry. Dr. Oda’s research interests include molecular changes in oral carcinogenesis and HPV and oral cancer. She has 70 papers published in refereed journals and publishes a popular monthly column called Case of the Month. Dr. Oda is a diplomate of the American Board of Oral and Maxillofacial Pathology and holds a Washington State dental license. She is also a member of the American Academy of Oral and Maxillofacial Pathology, the International Association of Oral Pathologists, and USCAP.

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The University of Washington is an ADA CERP Recognized Provider.
ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry.

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The University of Washington is a member of the Association for Continuing Dental Education.

University of Washington designates this activity for 2 continuing education credits.