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Fritzie Arce-McShane, PhD

Fritzie Arce-McShane

Assistant Professor, Oral Health Sciences



Dr. Arce-McShane is an Assistant Professor in the Department of Oral Health Sciences. She received her Bachelor of Science in Physical Therapy from the University of the Philippines, Master of Arts in Motor Learning from Columbia University in New York, and PhD in Neuroscience from the Hebrew University of Jerusalem in Israel. She did her postdoctoral work at the University of Chicago and was a Research Assistant Professor prior to joining the School of Dentistry in November 2021.

Research Interests

Dr. Arce-McShane is a neuroscientist and her research focuses on the principles of cortical and biomechanical control of oral sensorimotor behavior (such as feeding, breathing and speech), and how these are affected by learning, aging, and disease. Her previous background as a physical therapist with strong concentrations in movement science, neurological and cognitive rehabilitation has given her a keen awareness of patients’ problems and needs. Her basic science research draws from her clinical experience and is aimed  towards innovative research that directly impacts the evaluation and treatment of neurodegenerative diseases, sensorimotor disorders, restoration of sensory feedback in brain-machine interfaces, and age-related dementias.

Her lab uses a multidisciplinary approach to understand the interplay between sensation and movement using converging evidence from psychophysics, biomechanics, neurophysiology, and computational modeling. Her methods include recording neural activity from chronically-implanted microelectrode arrays in multiple regions of the cerebral cortex simultaneous with recording the movements of the tongue and the mandible using high-resolution biplanar radiography and applying computational models to understand the principles of sensorimotor control.

Research Lab website

Selected Publications

  1. Arce-McShane FI (2021) The association between age-related changes in oral neuromechanics and Alzheimer’s disease. Adv Geriatr Med Res 2021;3(2):e210011.
  2. Laurence-Chasen J, Manafzadeh AR, Hatsopoulos NG, Ross CF, Arce-McShane FI (2020) Integrating XMALab and DeepLabCut for high-throughput XROMM. Journal of Experimental Biology 2020 223: jeb226720 doi: 10.1242/jeb.226720
  3. Arce-McShane FI, Sessle BJ, Ram Y, Takahashi K, Balcer C, Ross CF, Hatsopoulos NG (2020) Multiple regions of primate orofacial sensorimotor cortex encode bite force and gape. bioRxiv doi:
  4. Arce-McShane FI, Sessle BJ, Ross CF, Hatsopoulos NG (2018) Primary sensorimotor cortex exhibits complex dependencies of spike-field coherence on neuronal firing rates, field power, and behavior. Journal of Neurophysiology 120 (1):226-238
  5. Arce-McShane FI, Takahashi K, Ross CF, Sessle BJ, Hatsopoulos NG (2016) Primary motor and sensory cortical areas communicate via spatiotemporally coordinated networks at multiple frequencies. Proceedings of National Academy of Sciences 113(18):5083-5088
  6. Arce-McShane F, Hatsopoulos NG, Lee JC, Ross CF, Sessle BJ (2014) Modulation dynamics in the orofacial sensorimotor cortex during motor skill acquisition. Journal of Neuroscience 34(17):5985-5997
  7. Arce F, Ross CF, Lee JC, Sessle BJ, Hatsopoulos NG (2013) Directional information from neuronal ensembles in the primate orofacial sensorimotor cortex. Journal of Neurophysiology 110(6):1357-1369

Recent Conference Poster Presentations

  1. Sheridan L, Laurence-Chasen JD, Arce-McShane FI (2021). Sensory loss affects multi-region neural network dynamics in primate sensorimotor cortex. 2021 Society for Neuroscience Conference (accepted)
  2. Luckas J, Laurence-Chasen JD, Fereira III H, Arce-McShane FI (2021). Novel biomarkers in healthy aging: Tongue and jaw kinematics as a potential way to further explore Alzheimer’s-induced biological changes. 2021 Alzheimer’s Association International Conference
  3. Tang D, Simonoff A, Laurence-Chasen JD, Arce-McShane FI (2021) Decoding lingual-palatal contacts from population responses in primate orofacial sensorimotor cortex. Computational and Systems Neuroscience (Cosyne) 2021
  4. Tang D, Simonoff A, Laurence-Chasen JD, Sessle B, Ross C, Hatsopoulos NG, Arce-McShane FI (2021) Decoding lingual-palatal contacts from population responses in primate orofacial sensorimotor cortex. Society for Neuroscience Global Connectome
  5. Laurence-Chasen JD, Ross CF, Hatsopoulos NG, Arce-McShane F (2021) Decoding tongue position and shape from population responses in primate orofacial sensorimotor cortex. Society for Neuroscience Global Connectome
  6. Laurence-Chasen JD, Manafzadeh AR, Hatsopoulos NG, Ross CF, Arce-McShane F (2021) XROMM Tools for DeepLabCut: Bringing deep learning to XROMM marker tracking. Virtual Society for Integrative and Comparative Biology