Dr. Chung

Dr. Chung

Whasun “Sun” Oh Chung, PhD

Office: B-147
Lab: B-149
Box: 357132
Email: sochung@uw.edu


Research Associate Professor, Oral Health Sciences
Director, Summer Research Fellowship, School of Dentistry

Interests

  • Gingival innate immunity to commensal vs. pathogenic bacteria
  • Titanate-metal complexes as new antimicrobials in dentistry
  • Epigenetic regulations in oral health and disease
  • Differential utilization of signaling pathways in oral innate immune regulation
  • Cross-communication between epithelial cell receptors in innate immune responses
  • Role of protease inhibitors in periodontal health and disease
  • Regulation of human beta-defensins in oral epithelial cells

Current Courses

  • DENT 550B – Research Methods (Director)
  • ORALB 520 – Molecular Microbiology and Oral Diseases (Participating Faculty)
  • ORALB 579 – Molecular biology (Participating Faculty)

Publications

  1. Kretschmar, S., L. Yin, F.A. Roberts, R. London, T.T. Flemmig, D. Arushanov, K. Kaiyala and W.O. Chung.  2011.  Protease inhibitor levels in periodontal health and disease.  Journal of Periodontal Research, E-published 2011 Oct 27.
  2. Chung, W.O., J. Wataha, D. Hobbs, J. An, J. Wong, C. Park, S. Dogan, M. Elvington and B. Rutherford.  2011.  Peroxotitanate and monosodium metal-titanate compounds as inhibitors of bacterial growth.  Journal of Biomedical Materials Research, 97(3):348-354.
  3. Yin, L., and W.O. Chung.  2011.  Epigenetic regulation of gingival innate immune responses to oral bacteria.  Mucosal Immunology, 4(4):409-419.
  4. Rohani,M.G., D.H. DiJulio, J.A. An, B.M. Hacker, B.A. Daleand W.O. Chung.  2010.  PAR1- and PAR2-induced innate immune markers are negatively regulated by PI3K/Akt signaling pathway in oral keratinocytes.  BMC Immunology, 11:53, E-published 2010 Oct 28.
  5. Yin, L., T. Chino, O.V. Horst, B.M. Hacker, E.A. Clark, B.A. Dale and W.O. Chung.  2010.  Differential and coordinated expression of defensins and cytokines by gingival epithelial cells and dendritic cells in response to oral bacteria.  BMC Immunology, 11:37.  E-published 2010 Jul 9.
  6. Yin, L., B. Swanson, J. An, B.M. Hacker, G.A. Silverman, B.A. Dale and W.O. Chung.  2010.  Differential effects of periopathogens on host protease inhibitors SLPI, elafin, SCCA1, and SCCA2.  Journal of Oral Microbiology. E-published 2010 May 4.
  7. Chung, W.O., J. An, L. Yin, B.M. Hacker, M.G. Rohani, H. Dommisch, and D.H. DiJulio.  2010.  Interplay of Protease-activated receptors and nucleotide-binding oligomerization domain in gingival epithelial innate immune responses.  Immunology Letters, 131(2):113-9.
  8. Rohani,M.G.,R.P. Beyer, B.M. Hacker, H. Dommisch, B.A. Daleand W.O. Chung.  2010.  Modulation of expression of innate immunity markers CXCL5/ENA-78 and CCL20/MIP3α by Protease-activated Receptors (PARs) in human gingival epithelial cells.  Innate Immunity,16(2):104-14.

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