UW School of Dentistry

PBIO 505

Human Physiology

Marc Binder

4 Credits / Quarter 1 (Autumn, First Year)

Course Description

Intensive coverage of physiology through lectures and conferences. Excitable tissues, skeletal muscles; spinal reflex; pain physiology; endocrinology; autonomic nervous system; reproductive endocrinology.

Educational Objectives

The student will gain knowledge in the principles of physiology and biophysics. The objectives will be for the student to be able to explain (1) the physiology of excitable cells, (2) muscle contraction, mechanisms and energetics, (3) spinal reflex, (4) autonomic nervous system (5) mechanism of hormone action (6) sexual differentiation (7) basic reproductive endocrinology

Course Outline

Lecture topics include: excitable cells, impulse generation and propagation, synaptic transmission, receptors, muscle and the molecular basis of contraction, muscle mechanics and energetics, spinal reflex, autonomic nervous system, physiology of pain, types of hormones, mechanism of hormone action, calcium homeostasis, hormonal control of metabolism, sexual differentiation, adult male reproductive physiology, adult female reproductive physiology.

Course Expectations

To successfully meet the requirements of this course, the student must attend all lectures and demonstrate his/her understanding of lecture topics and assigned readings through satisfactory performance on two (2) midterms and one final examination.


Human Physiology: An integrated approach. 4th Edition, 2007.

*last updated: 11/7/2011